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The main active substance of krokodil is referred to be a semi-synthetic opioid derivative from morphine, called desomorphine (C 17 H 21 NO 2, dihydrodesoxymorphine) (Fig. 1).Chemically, desomorphine is a white to light beige solid at room temperature, with a molecular weight of 271.35 g/mol and a melting point of 189 °C.It is a stable powder when stored under adequate conditions and an.
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Krokodil has roughly the same effect as heroin but is at least three times cheaper and extremely easy to make. The active component is codeine, a widely sold over-the-counter painkiller that is.
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Krokodil is a derivative of codeine that is intravenously abused as a cheap substitute for heroin. It has sedative and pain-relieving effects, is highly addictive, and can lead to gangrene that resembles a crocodile's skin.. Due to the drug's rapid onset but short duration of action and frequent administration, quick physical dependence.
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Desomorphine is the common name for 4,5-α-epoxy-17-methylmorphinan-3-ol or dihydrodesoxymorphine-D. It is an opioid analogue and morphine derivative in which the 6-hydroxyl group and the double bond at carbons 7 and 8 of morphine are reduced (Small and Morris, 1933).Chemically, desomorphine (C 17 H 21 NO 2) is a colorless, well-crystallized organic base such as morphine and other alkaloids.
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Use of "Krokodil," a deadly Russian designer drug, has been spreading rapidly across Europe.1,2 It can turn an addict's skin dark, scaly, and necrotic and cause it to wither away. "Krokodil" use was first reported in Siberia in 2002 and so far has been reported only in European countries.3 Our case aims to shed light on the alarming fact that this deadly mixture has made its way into.
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Krokodil Drug Effects. Krokodil is attractive to those seeking a euphoric high because it is cheap, relatively easy to make or obtain, produces a high similar to that of heroin, and delivers potent sedative and pain-relieving effects in the user. Krokodil's effects have a very fast onset of about 2-3 minutes and last for approximately 2 hours.
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Krokodil, also known as the zombie drug, has effects similar to opiates, yet it can be more dangerous and deadly. Krokodil (or the "zombie drug") is a street name for desomorphine. Krokodil drug abuse was relatively unheard of in the U.S. until fairly recently, but the drug has been problematic in Russia and other former Soviet countries.
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Discover the shocking and deadly world of Krokodil, a homemade opioid with devastating effects. Learn how it emerged, its gruesome consequences, and its spre.
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Krokodil (desomorphine) is a dangerous and potentially fatal drug that causes a number of side effects, including scaly, green and black skin that resembles an alligator. Here's what makes it so.
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Krokodil, a cheap substitute for heroin, was one of the deadliest designer drugs ever to sweep through Russia. Appearing on the black market in the early 2000s, it wound up ensnaring hundreds of.
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Krokodil is the street name for the drug desomorphine, a particularly dangerous illicit drug with an opioid-like mechanism of action that is 10 times more potent than morphine.[1] While it would be dangerous enough for its opioid-like effects, it can also cause quite serious health effects not typical of opioids, including severe tissue damage.
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Krokodil production probably emerged in Siberia and Eastern Russia about 15 years ago [4,5]. In May 2004, it was reported for the first time the description of Krokodil abuse, in the Republic of Komi, and in 2008, 5.000 Krokodil consumers were reported, out of a total estimated population of 20.000- 30.000.
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But during the time between concerns being raised and any action krokodil reached epidemic proportions. Russian seizures of krokodil drug grew by 40 times from two kilograms in 2006 to 100 kilograms in 2011. In June 2012, after a year of debates, the Russian government finally restricted access to codeine-containing medications.